The gun has a firing pin block so if you lowered all the way down, should be no issue.
Up to you where you want to place it on the half cock or the full down position for carry.
For competition , the rule for USPSA Production and IDPA SSP is the pistol must be in the fully decocked position for the start.
for safety model guns that is fully down. for decockers that is the halfcock where it drops it.